Clinical Trials - should I or not?

Met with Dr. Kim o - She is encouraging me to join a clinical trial program where i would have a 50/50 chance of getting a shot that ‘could’ prevent the recurrence of prostate cancer in the bones.  One group gets calcium supplements, the other group gets supplements AND a shot.   She informed me that the cancer WILL come back, and when it does it will be in my bones.  I thought she was pretty blunt about that, and wondered her motives, was she trying to scare me into the trials?   My wife and I had already decided against it as the patient is responsible for expenses that insurance (medicare) either will or will not pick up. Possible side effects were quite extensive.  We had even thrown the paperwork away.  We told her we would reconsider… she is quite persuasive.
My repeated question to her way - why don’t you just give me the shot?  Why do I have to go through the trial and have a 50/50 chance of getting it?
Her answer “We don’t know if it work or not”
so what - it isn’t going to hurt me - give it to me anyway.
I still dont understand that.
I also found out my cancer is Stage Two.

Week Two

although delayed on appt Monday - treatments continuing.  Meeting people at the cancer clinic and at the hospital and sharing our stories.  The cancer clinic supplied a discount card for the hospital cafeteria.  Food isn’t very good - but it’s cheap
Feeling a little peaked after wednesday’s treatment.  Stomach is upset and lightheadedness.

 

Gleason Score

The Gleason Score

Prostate cancer is the second most deadly form of cancer in males next to lung cancer. It can strike men in their fifties and may not be detected until it’s too late. A Gleason Score was developed to help evaluate the stages of prostate cancer and to determine prognosis and to guide therapy.

A Gleason Score is given to grade prostate cancer. The scale numbers from 1-5. The Gleason Score numbers from 2-10. The lower the score, the better prognosis, the higher score means the cancer is more aggressive and the prognosis is worse. The Gleason Score was named after Donald F. Gleason, M.D. who was a pathologist at the Minneapolis V.A. Hospital. It was developed in the 1960’s to help determine the level of cancerous cells present after a biopsy.

To determine the grade of prostate cancer a urologist will take a biopsy of prostate tissue through the rectum, it will then be prepared for examination by a pathologist. They will give the biopsy a grade.

Grade 1: cells are close together and resemble normal prostate tissue
Grade 2: cells are larger and have more space between them.
Grade 3: cells are darker but have left the glands and are beginning to surround other tissue.
Grade 4: cells have left the glands but are still recognizable; they are surrounding and invading other tissue.
Grade 5: cells are unrecognizable and have sheets of cancerous cells throughout the surrounding tissue.

A Gleason Score is the combination of two patterns, the cell tissue and the cancerous tissue. The grades are added to the score to determine the proper course of treatment which could range from chemotherapy to surgery. Prostate cancer is metastasizing cells, which means in can invade other parts of the body such as the bladder, bones and rectum.
Early detection is always the key and many men over fifty should get a checkup to determine if any cancerous cells have developed.

Implanting the markers

Yesterday he had the fiduciaries (sp?) implanted in his prostate.  It was not a pleasant procedure.  Be sure to make sure to check that they’ve lubed up the apparatus before they insert it!  It didn’t really take too long.   He was able to have a nice lunch afterwards and drive home.

There was quite a bit of bleeding - both during and afterwards.  Seems to have stopped today.

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